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Publications

Publications (2018-2024) by DRB Graduate Students

Names of the DRB students are underlined.

  • Matsushige C, Kitazumi K, Beaman A, Miyagi M, Tallquist MD, Yamazaki Y. RGD peptide promotes follicle growth through integrins αvβ3/αvβ5 in three-dimensional culture. Reproduction. 2024 Dec 9;169(1):e240151. doi: 10.1530/REP-24-0151. PMID: 39441765.
  • Nunes LGA, Rosario FJ, Urschitz J. In vivo placental gene modulation via sonoporation. Placenta. 2024 Oct 23:S0143-4004(24)00688-X. doi: 10.1016/j.placenta.2024.10.015. Epub ahead of print. PMID: 39477696.
  • Wu H, Nguyen H, Hashim PH, Fogelgren B, Duncan FE, Ward WS. Oocyte-specific EXOC5 expression is required for mouse oogenesis and folliculogenesis. Mol Hum Reprod. 2024 Aug 5;30(8):gaae026. doi: 10.1093/molehr/gaae026. PMID: 39037927.
  • Padron JG, Saito Reis CA, Ng PK, Norman Ing ND, Baker H, Davis K, Kurashima C, Kendal-Wright CE. Stretch Causes cffDNA and HMGB1-Mediated Inflammation and Cellular Stress in Human Fetal Membranes. Int J Mol Sci. 2024 May 9;25(10):5161. doi: 10.3390/ijms25105161.
  • Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. Nucleic Acids Res. 2024 Aug 12;52(14):e64. doi: 10.1093/nar/gkae534. PMID: 38953167.
  • Cheung EC, Nilsson A, Venter I, Kowalik G, Ribeiro C, Rodriguez J, Kuraoka K, Russo R, Escobar JB, Alber BR, Mendelowitz D, Kay MW, Schunke KJ. Sex differences in cardiac transcriptomic response to neonatal sleep apnea. Physiol Rep. 2024 Jul;12(13):e16110. doi: 10.14814/phy2.16110. PMID: 38981849.
  • Nunes LGA, Ma C, Hoffmann FW, Shay AE, Pitts MW, Hoffmann PR. Selenoprotein I is indispensable for ether lipid homeostasis and proper myelination. J Biol Chem. 2024 Apr 4:107259. doi: 10.1016/j.jbc.2024.107259. PMID: 38582453.
  • Torigoe TH, Willcox DC, Shimabukuro M, Higa M, Gerschenson M, Andrukhiv A, Suzuki M, Morris BJ, Chen R, Gojanovich GS, Allsopp RC, Willcox BJ. Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans. NPJ Aging. 2024 Mar 8;10(1):18. doi: 10.1038/s41514-024-00142-8. PMID: 38459055.
  • Huntsman MC, Kurashima CK, Marikawa Y. Validation of a mouse 3D gastruloid-based embryotoxicity assay in reference to the ICH S5(R3) guideline chemical exposure list. Reprod Toxicol. 2024 Feb 15;125:108558. doi: 10.1016/j.reprotox.2024.108558. PMID: 38367697.

  • Holmlund H, Yamauchi Y, Ruthig VA, Cocquet J, Ward MA. Return of the forgotten hero: the role of Y chromosome-encoded Zfy in male reproduction. Mol Hum Reprod. 2023 Jul 31;29(8):gaad025. doi: 10.1093/molehr/gaad025. PMID: 37354519.
  • Nguyen H, Ribas-Maynou J, Wu H, Quon B, Inouye T, Walker B, Langaman C, Huang TTF, Ward WS. Low levels of mouse sperm chromatin fragmentation delay embryo development. Biol Reprod. 2023 Sep 2:ioad106. doi: 10.1093/biolre/ioad106. Epub ahead of print. PMID: 37658763.
  • Ribas-Maynou J, Nguyen H, Wu H, Ward WS. Functional Aspects of Sperm Chromatin Organization. Results Probl Cell Differ. 2022;70:295-311. doi: 10.1007/978-3-031-06573-6_10. PMID: 36348112; PMCID: PMC9671218.
  • Padron JG, Norman Ing ND, Ng PK, Kendal-Wright CE. Stretch Causes Cell Stress and the Downregulation of Nrf2 in Primary Amnion Cells. Biomolecules. 2022 May 31;12(6):766. doi: 10.3390/biom12060766. PMID: 35740891; PMCID: PMC9220942.
  • Saito Reis CA, Ng PK, Kurashima CK, Padron J, Kendal-Wright CE. Fetal DNA Causes Sex-Specific Inflammation From Human Fetal Membranes. Front Physiol. 2022 Jun 22;13:901726. doi: 10.3389/fphys.2022.901726. PMID: 35812324; PMCID: PMC9257279.
  • Kurashima CK, Ng PK, Kendal-Wright CE. RAGE against the Machine: Can Increasing Our Understanding of RAGE Help Us to Battle SARS-CoV-2 Infection in Pregnancy? Int J Mol Sci. 2022 Jun 7;23(12):6359. doi: 10.3390/ijms23126359. PMID: 35742804; PMCID: PMC9224312.
  • Nguyen TB, Lac Q, Abdi L, Banerjee D, Deng Y, Zhang Y. Harshening stem cell research and precision medicine: The states of human pluripotent cells stem cell repository diversity, and racial and sex differences in transcriptomes. Front Cell Dev Biol. 2023 Jan 4;10:1071243. doi: 10.3389/fcell.2022.1071243. PMID: 36684445; PMCID: PMC9848738.
  • Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert WA, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy SV, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. PLoS Pathog. 2023 May 18;19(5):e1011409. doi: 10.1371/journal.ppat.1011409. PMID: 37200377; PMCID: PMC10231791.
  • Ribas-Maynou J, Nguyen H, Valle R, Wu H, Yeste M, Ward WS. Sperm degradation after vasectomy follows a sperm chromatin fragmentation-dependent mechanism causing DNA breaks in the toroid linker regions. Mol Hum Reprod. 2022 Aug 29;29(9):gaac029. doi: 10.1093/molehr/gaac029. PMID: 35929777; PMCID: PMC9422300.
  • Morosky P, Comyns C, Nunes LGA, Chung CZ, Hoffmann PR, Soll D, Vargas-Rodriguez O and Krahn N (2023) Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins. Frontiers in Molecular Biosciences 10:1096261. doi: 10.3389/fmolb.2023.1096261.
  • Kirkwood-Johnson L, Marikawa Y. (2023) Developmental toxicity of remdesivir, an anti-COVID-19 drug, is implicated by in vitro assays using morphogenetic embryoid bodies of mouse and human pluripotent stem cells. Birth Defects Research 115(2):224-239. doi: 10.1002/bdr2.2111. PMCID: PMC9877128

  • Fernandes VFL, Glaser Y, Iwashita M, Yoshizawa M. (2022) Evolution of left-right asymmetry in the sensory system and foraging behavior during adaptation to food-sparse cave environments. BMC Biology 20(1):295. doi: 10.1186/s12915-022-01501-1. PMID: 36575431; PMCID: PMC9795734.
  • Yang X*, Kawasaki NK*, Min J, Matsui T, Wang F. (2022) Ferroptosis in heart failure. J Mol Cell Cardiol. Oct 20;173:141-153. doi: 10.1016/j.yjmcc.2022.10.004. PMID: 36273661. (*co-first authors)
  • Komai K, Kawasaki NK, Higa JK, Matsui T. The Role of Ferroptosis in Adverse Left Ventricular Remodeling Following Acute Myocardial Infarction. Cells. 2022 Apr 20;11(9):1399. doi: 10.3390/cells11091399. PMID: 35563704; PMCID: PMC9102292.
  • Holmlund H, Yamauchi Y, Durango G, Fujii W, Ward MA. (2022): Two recently acquired mouse Y chromosome-linked genes, Prssly and Teyorf1, are dispensable for male fertility. Biology of Reproduction. 2022 Apr 29:ioac084. doi: 1093/biolre/ioac084.
  • Matsushige C, Xu X, Miyagi M, Zuo YY, Yamazaki Y. (2022) RGD-modified dextran hydrogel promotes follicle growth in three-dimensional ovarian tissue culture in mice. Theriogenology. Apr 15;183:120-131.
  • Urena F, Ma C, Hoffmann FW, Nunes LGA, Urschitz J, Moisyadi S, Khadka VS, Deng Y, Hoffmann PR. (2022) T-cell activation decreases miRNA-15a/16 levels to promote MEK1-ERK1/2-Elk1 signaling and proliferative capacity. J Biol Chem. Jan 25;298(3):101634.
  • Yamauchi Y, Matsumura T, Bakse J, Holmlund H, Blanchet G, Carrot E, Ikawa M, Ward MA. (2022) Loss of mouse Y chromosome gene Zfy1 and Zfy2 leads to spermatogenesis impairment, sperm defects, and infertility. Biology of Reproduction. Mar 16:ioac057. doi: 10.1093/biolre/ioac057.
  • Nguyen H, Wu H, Ung A, Yamazaki Y, Fogelgren B, Ward WS.(2022) Deletion of Orc4 during oogenesis severely reduces polar body extrusion and blocks zygotic DNA replication. Biology of Reproduction. 106(4):730-740.
  • Nakamatsu NA, Aytaç G, Mikami B, Thompson JD, Davis M 3rd, Rettenmeier C, Maziero D, Andrew Stenger V, Labrash S, Lenze S, Torigoe T, Lozanoff BK, Kaya B, Smith A, Douglas Miles J, Lee UY, Lozanoff S. (2022) Case-based radiological anatomy instruction using cadaveric MRI imaging and delivered with extended reality web technology. Eur J Radiol. 146:110043.

  • Kirkwood-Johnson L, Katayama N, Marikawa Y. (2021) Dolutegravir impairs stem cell-based 3D morphogenesis models in a manner dependent on dose and timing of exposure: an implication for its developmental toxicity. Toxicol Sci. 184(2):191-203.
  • Frankum R, Jameson TSO, Knight BA, Stephens FB, Wall BT, Donlon TA, Torigoe T, Willcox BJ, Willcox DC, Allsopp RC, Harries LW. (2021) Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels. Geroscience. doi: 10.1007/s11357-021-00431-0.
  • Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N.(2021) Disrupted glucose homeostasis and skeletal muscle-specific glucose uptake in an exocyst knockout mouse model. Am J Reprod Immunol. 85(1):e13328.
  • Saito Reis CA, Padron JG, Norman Ing ND, Kendal-Wright CE.(2021) High-mobility group box 1 is a driver of inflammation throughout pregnancy. J Biol Chem. 296:100482.
  • Freemyer BG, Urbi A, Torigoe T, Stickley C.(2021) Weight-Bearing Versus Traditional Strength Assessments of the Hip Musculature. J Athl Train. 56(2):191-6.

  • Li ASW, Marikawa Y.(2020) Methoxyacetic acid inhibits histone deacetylase and impairs axial elongation morphogenesis of mouse gastruloids in a retinoic acid signaling-dependent manner. Birth Defects Research. Aug;112(14):1043-1056.
  • Padron JG, Saito Reis CA, Kendal-Wright CE.(2020) The Role of Danger Associated Molecular Patterns in Human Fetal Membrane Weakening. Front Physiol. 2020 Jun 17;11:602.

  • Mishra PK, Adameova A, Hill JA, Baines CP, Kang PM, Downey JM, Narula J, Takahashi M, Abbate A, Piristine HC, Kar S, Su S, Higa JK, Kawasaki NK, Matsui T. (2019) Guidelines for evaluating myocardial cell death. Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H891-H922.
  • Worsham M, Fernandes VFL, Settle A, Balaan C, Lactaoen K, Tuttle LJ, Iwashita M, Yoshizawa M. (2019) Behavioral Tracking and Neuromast Imaging of Mexican Cavefish. Journal of Visualized Experiments Apr 6;(146):10.3791/59099. doi: 10.3791/59099.
  • Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N.(2019) The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. American Journal of Physiology (Endocrinology and Metabolism). doi: 10.1152/ajpendo.00109.2019. [Epub ahead of print]
  • Hew BE, Sato R, Mauro D, Stoytchev I, Owens JB.(2019) RNA-guided piggyBac transposition in human cells. Synthetic Biology (Oxford, England). 4:ysz018.
  • Riel JM, Yamauchi Y, Ruthig VA, Malinta QU, Blanco M, Moretti C, Cocquet J, Ward MA. (2019) Rescue of Sly Expression Is Not Sufficient to Rescue Spermiogenic Phenotype of Mice with Deletions of Y Chromosome Long Arm. Genes 10. pii: E133.
  • Ortega EA, Salvador Q, Fernandez M, Ward MA. (2019) Alterations of sex determination pathway in the genital ridges of males with limited Y chromosome genes. Biology of Reproduction 100:810-823.
  • Balaan C, Corley MJ, Eulalio T, Leite-Ahyo K, Pang APS, Fang R, Khadka VS, Maunakea AK, Ward MA. (2019) Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder. Behavioural Brain Research 356:137-147.

  • Fernandes VFL, Macaspac C, Lu L, Yoshizawa M. (2018) Evolution of the developmental plasticity and a coupling between left mechanosensory neuromasts and an adaptive foraging behavior. Developmental Biology 441(2):262-271.
  • Warkus EL, Marikawa Y. (2018) Fluoxetine inhibits canonical Wnt signaling to impair embryoid body morphogenesis: potential teratogenic mechanisms of a commonly used antidepressant. Toxicological Sciences 165(2):372-388.
  • Davy PMC, Willcox DC, Shimabukuro M, Donlon TA, Torigoe T, Suzuki M, Higa M, Masuzaki H, Sata M, Chen R, Murkofsky RL, Morris BJ, Lim E, Allsopp RC, Willcox BJ. (2018) Minimal shortening of leukocyte telomere length across age groups in a cross-sectional study for carriers of a longevity-associated FOXO3 allele. The Journals of Gerontology 73(11):1448-1452.
  • Kim IQ, Marikawa Y. (2018) Embryoid body test with morphological and molecular endpoints implicates potential developmental toxicity of trans-resveratrol. Toxicology and Applied Pharmacology 355:211-225.